منابع مشابه
Cysteine suppresses oxidative stress-induced myofibrillar proteolysis in chick myotubes.
The effects of cysteine as an antioxidant nutrient on change in protein modification and myofibrillar proteolysis in chick myotubes by induction of oxidative stress by H(2)O(2) treatment were investigated. Myotubes were treated for 1 h with H(2)O(2) (1 mM). After this treatment, the H(2)O(2) was removed and the cells were cultured in cysteine (0.1 and 1 mM) containing serum-free medium for 24 h...
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Yeasts are nowadays relevant microorganisms in both biotechnology, with important economic impact in several fields, and fundamental research where Saccharomyces cerevisiae appears as one of the most used and versatile eukaryotic cell models. In industrial fermentations, yeasts are subjected to different stress conditions, such as those imposed by low water activity and by the presence of cytot...
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Critically impaired protein degradation is discussed to contribute to neurodegenerative disorders, including Parkinson's, Huntington's, Alzheimer's, and motor neuron diseases. Misfolded, aggregated, or surplus proteins are efficiently degraded via distinct protein degradation pathways, including the ubiquitin-proteasome system, autophagy, and vesicular trafficking. These pathways are regulated ...
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Doxorubicin (Dox) is a potent antitumor agent used in cancer treatment. Unfortunately, Dox is myotoxic and results in significant reductions in skeletal muscle mass and function. Complete knowledge of the mechanism(s) by which Dox induces toxicity in skeletal muscle is incomplete, but it is established that Dox-induced toxicity is associated with increased generation of reactive oxygen species ...
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ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 2006
ISSN: 0950-382X
DOI: 10.1111/j.1365-2958.1992.tb01419.x